Combining allele frequency uncertainty and population substructure corrections in forensic DNA calculations
نویسندگان
چکیده
منابع مشابه
Genotype and allele frequency of CYP2C19*17 in a healthy Iranian population
Background: Cytochrome P450 2C19 (CYP2C19) is important in metabolism of wide range of drugs. CYP2C19*17 is a novel variant allele which increases gene transcription and therefore results in ultra-rapid metabolizer phenotype (URM). Distribution of this variant allele has not been well studied worldwide. The aim of present study was to investigate allele and genotype frequencies of CYP2C19*17 ...
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15 صفحه اولFrequency of CCR5Δ32 allele in healthy Bosniak population.
Recent evidence has demonstrated the role of CCR5Δ32 in a variety of human diseases: from infectious and inflammatory diseases to cancer. Several studies have confirmed that genetic variants in chemokine receptor CCR5 gene are correlated with susceptibility and resistance to HIV infection. A 32-nucleotide deletion within the CCR5 reading frame is associated with decreased susceptibility to HIV ...
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ژورنال
عنوان ژورنال: Forensic Science International: Genetics
سال: 2016
ISSN: 1872-4973
DOI: 10.1016/j.fsigen.2016.05.006